California Tumor Tissue Registry http://www.cttr.org/cms Wed, 01 Sep 2010 05:00:21 +0000 http://backend.userland.com/rss092 en September 2010: A 31 year old man with immunodeficiency and cervical lymphadenopathy History: A 31 y/o physician with a retroviral disease and associated immunodeficiency was found to have cervical lymphadenopathy. He had a chronic cough, but sputum had been negative for mycobacterium and PCP. There was no evidence of fungal or acid fast bacilli. No skin lesions were found and there was no history of previous neoplasia. Excisional lymph node biopsy was performed. The specimen was received in multiple fragments (Fig. 1)

Microscopically the normal lymph node architecture was replaced by a disordered vascular proliferation (Fig. 2). The cells were spindled and showed a diffuse fascicular pattern (More

]]> http://www.cttr.org/cms/?p=460 August 2010: A 28 year old man with a long-standing epigastric mass History: A 28-year-old male presented with a left epigastric mass that had been present for ten years. During exploratory surgery, a 15 cm mass was excised from the greater omentum. It was gray-tan with a heterogeneous surface.

The tumor showed a peculiar trabecular growth pattern (Fig. 1), consisting of cohesive, small, polygonal to round blue cells, sometimes nested, with a prominent supporting desmoplastic stroma (Fig. 2). At the periphery of the tumor the tumor grew in nests and single files (Fig. 3). A subtle but substantial vascular network was seen (Fig. 3).… More

]]> http://www.cttr.org/cms/?p=458 Site recovered We seemed to have recovered from a “hack attack” from this last week (or at least Google and stopbadware are finally unblocking us) after much poring over and reinstalling of files.

Preventive steps have also been taken. Hopefully this will calm things down for awhile.

]]> http://www.cttr.org/cms/?p=707 Forms appear to be working again Noticed a problem with the online forms. [apparently a problem again, after having cleaned up a bunch of hacker injected code and re-uploaded the form scripts, ed. Forms will be offline until further notice].

If you have submitted any forms between July 1st and 6th, please resubmit them by email. Thanks.

Update: Forms appear to be working after turning off Ajax.

]]> http://www.cttr.org/cms/?p=709 July 2010: A 50 year old woman with a mass in the toe History: A 50-year-old female school teacher presented with a two year history of swelling of the right third toe. X-rays were read as being commensurate with a malignant tumor (Fig. 1), and an en-bloc resection of the third ray was performed. A hard, multinodular, tan-gray 5.0 cm mass was found to primarily involve the proximal phalangeal bone and adjacent soft tissue.

Microscopic sections showed the tumor to break out of bone and to involve surrounding tissues with extension up to the deep dermis (Fig. 2). The tumor displayed an osseous matrix consisting mostly of woven and… More

]]> http://www.cttr.org/cms/?p=456 May 2010 Case 1: Breast showing Rx effects (irradiation)
Case 2: Papillomatosis, breast
Case 3: Microglandular adenosis/nodular adenosis, breast
Case 4: Juvenile fibroadenoma, breast
Case 5: Ductal carcinoma in situ (DCIS), breast
Case 6: Medullary carcinoma, breast
Case 7: Metaplastic carcinoma, breast
Case 8: Phyllodes tumor, breast
Case 9: Mucinous carcinoma, breast
Case 10: Metastatic melanoma, breast

]]> http://www.cttr.org/cms/?p=675 May 2010 Case 1: High grade urothelial carcinoma, invasive, bladder
T-74000, M-81203
Case 2: Mixed germ cell tumor/mature & immature teratoma, testis
T-78000, M-86310
Case 3: Xanthogranulomatous pyelonephritis
T-71000, M-44070
Case 4: Cystic nephroma (multilocular cyst), kidney
T-71000, M-89601
Case 5: Clear cell renal cell carcinoma, kidney
T-71000, M-83123
Case 6: Mucinous tubular and spindle cell carcinoma, kidney
T-71000, M-80323
Case 7: Wilms tumor (nephroblastoma), favorable histology, kidney
T-71000, M-89603
Case 8: Complex basal cell hyperplasia, prostate
T-77100, M-72120
Case 9: High grade prostatic adenocarcinoma (ductal/”endometrioid” pattern), Gleason 5+5, prostate
T-77100, M-83803
Case 10: Mucinous (colloid) adenocarcinoma, prostate
T-77100, M-84803

]]> http://www.cttr.org/cms/?p=673 May 2010 Case 1: Giant cell tumor of tendon sheath, wrist
T-Y8600, M-92501
Case 2: Spermatocytic seminoma, testis
T-78000, M-90633
Case 3: High grade neuroendocrine carcinoma, possibly variant of GIST, gastric fundus
T-6Y030, D-2040
Case 4: Merkel cell carcinoma (cutaneous small cell carcinoma), submental region
T-02156, M-80423
Case 5: High grade carcinoma with acinic features arising from a pleomorphic adenoma (“carcinoma ex-pleomorphic adenoma”), parotid
T-55120, M-85503
Case 6: Dedifferentiated liposarcoma (with “MFH” features), retroperitoneum
T-Y4600, M-88503
Case 7: Hepatocellular carcinoma, liver
T-56000, M-81703
Case 8: Small cell carcinoma,… More

]]> http://www.cttr.org/cms/?p=671 June 2010: A 44 year old man with a right hip mass History: An otherwise healthy 44-year-old man presented with a three month history of a painless lump over his right hip. Aspiration of the mass was dry, yielding no fluid. Surgical excision was performed, finding a 4.0 cm, smooth, pink, slightly glistening soft tissue tumor just proximal to the greater trochanteric region. The tumor was solid, without hemorrhage or necrosis.

Microscopically, the mass was composed mostly of thick, hypocellular collagenous tissue (Fig. 1). It was well-circumbscribed and minimally associated with adjacent soft tissue (Fig. 2). Widely interspaced within the collagen were stellate to spindle-shaped cells resembling fibroblasts… More

]]> http://www.cttr.org/cms/?p=454 April 2010 Case 1: Juvenile hyaline fibromatosis, elbow
Case 2: Rhabdomyosarcoma, paratesticular
Case 3: Fibrous Hamartoma of infancy, forearm
Case 4: Myopericytoma/Myofibroma, axilla
Case 5: Plexiform fibrohistiocytic neoplasm/Plexiform FH
Case 6: Giant cell fibroblastoma, abdominal wall
Case 7: Solitary Reticulohistiocytoma (Epithelioid histiocytoma)
Case 8: Nasopharyngeal angiofibroma, nasal sinus
Case 9: Cong neuroectodermal tumor (PNET), back & chest
Case 10: Ewing sarcoma, tibia

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